Lv7
4100 积分 2021-12-12 加入
Discovery of Highly Efficacious CRBN-Based KRAS Degraders Targeting Cancers with KRAS G12D and G12V Mutations
2天前
已完结
Discovery of 5-(Piperidin-4-yl)-1,2,4-oxadiazole Derivatives as a New Class of Human Caseinolytic Protease P Agonists for the Treatment of Hepatocellular Carcinoma
3天前
已完结
Development of Large-Scale Routes to Potent GPR119 Receptor Agonists
3天前
已完结
Enabling Process Development of Tetracyclic Quinolines for Brain-Penetrating KRAS G12C Inhibitors
3天前
已完结
Discovery of a Potent, Selective, and Orally Efficacious STAT6 PROTAC for the Treatment of Atopic Dermatitis
11天前
已完结
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
25天前
已完结
Discovery and Characterization of RP04340 : A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader
1个月前
已完结
Thousands of chemical starting points for antimalarial lead identification
1个月前
已完结
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
1个月前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
1个月前
已完结