Lv7
4230 积分 2021-12-12 加入
Discovery of (S)-1-((2′,6-Bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain
8天前
已完结
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers
8天前
已完结
Cutaneous Adverse Events Caused by Sulfonamide-Containing Drugs: Reality or Perception?
12天前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
23天前
已完结
Recent Developments in Cyclin-Dependent Kinase (CDK) PROTAC in Cancer Therapy
1个月前
已完结
Innovative medicinal chemistry strategies for enhancing drug solubility
1个月前
已完结
Indole therapeutics: Latest FDA updates, ongoing trials, and future directions
2个月前
已完结
Pyrazole-containing pharmaceuticals: target, pharmacological activity, and their SAR studies
2个月前
已完结
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor
2个月前
已完结
Promiscuity of in Vitro Secondary Pharmacology Assays and Implications for Lead Optimization Strategies
2个月前
已完结
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