Lv5
864 积分 2025-05-21 加入
Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice
18天前
已完结
RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo
18天前
已完结
Acyclic serinol nucleic acid modification of siRNAs overcomes seed region mediated off-target effects while maintaining potency
23天前
已完结
Improved specificity of gene silencing by siRNAs containing unlocked nucleobase analogs
28天前
已完结
Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo
28天前
已完结
Discovery of (S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic αvβ6 Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis
1个月前
已完结
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
1个月前
已完结
Ligand-bound integrin αvβ6 internalisation and trafficking
1个月前
已完结
Integrin αvβ6: Structure, function and role in health and disease
1个月前
已完结
Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants
1个月前
已完结
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