Lv7
4970 积分 2023-12-07 加入
Integrated Network Pharmacology and Experimental Validation to Elucidate the Mechanism of Celastrol in Mitigating Sepsis-induced Acute Lung Injury in mice
1个月前
已完结
Tanshinone IIA Attenuates Cerebral-Ischemia-Reperfusion-Induced Neuroinflammation by Inhibiting the TLR4/NF-κB Signaling Cascade: A Study Integrating Network Pharmacology, Bioinformatics, and Experimental Validation
1个月前
已完结
Piperine Improves Hyperuricemic Nephropathy by Inhibiting URAT1/GLUT9 and the AKT-mTOR Pathway
2个月前
已完结
Pharmacological evaluation of a novel skeleton compound isobavachin (4′,7-dihydroxy-8-prenylflavanone) as a hypouricemic agent: Dual actions of URAT1/GLUT9 and xanthine oxidase inhibitory activity
2个月前
已完结
Discovery of a Novel Thienopyrimidine Compound as a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability
2个月前
已完结
De Novo Design of HIV‐1 Integrase‐LEDGF/p75 Inhibitors Through Deep Reinforcement Learning and Virtual Screening
3个月前
已完结
Dual inhibition strategy addressing hyperuricemia and oxidative stress: design, biological evaluation and stability studies of febuxostat-probenecid mutual prodrug
4个月前
已完结
Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2020–present)
4个月前
已完结
Overview of the pharmacokinetics and pharmacodynamics of URAT1 inhibitors for the treatment of hyperuricemia and gout
4个月前
已完结
Design, synthesis and activity evaluation of novel lesinurad analogues containing thienopyrimidinone or pyridine substructure as human urate transporter 1 inhibitors
4个月前
已完结
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