Lv3
280 积分 2023-12-07 加入
Dual inhibition strategy addressing hyperuricemia and oxidative stress: design, biological evaluation and stability studies of febuxostat-probenecid mutual prodrug
2小时前
已完结
Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2020–present)
5天前
已完结
Overview of the pharmacokinetics and pharmacodynamics of URAT1 inhibitors for the treatment of hyperuricemia and gout
5天前
已完结
Design, synthesis and activity evaluation of novel lesinurad analogues containing thienopyrimidinone or pyridine substructure as human urate transporter 1 inhibitors
6天前
已完结
CDER167, a dual inhibitor of URAT1 and GLUT9, is a novel and potent uricosuric candidate for the treatment of hyperuricemia
19天前
已完结
Discovery of novel verinurad analogs as dual inhibitors of URAT1 and GLUT9 with improved Druggability for the treatment of hyperuricemia
19天前
已完结
Discovery of a Novel Thienopyrimidine Compound as a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability
19天前
已完结
Pharmacological evaluation of a novel skeleton compound isobavachin (4′,7-dihydroxy-8-prenylflavanone) as a hypouricemic agent: Dual actions of URAT1/GLUT9 and xanthine oxidase inhibitory activity
19天前
已完结
CarsiDock: a deep learning paradigm for accurate protein–ligand docking and screening based on large-scale pre-training
1个月前
已完结
Deep lead optimization enveloped in protein pocket and its application in designing potent and selective ligands targeting LTK protein
1个月前
已完结
A Self‐Powered Body Motion Sensing Network Integrated with Multiple Triboelectric Fabrics for Biometric Gait Recognition and Auxiliary Rehabilitation Training
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