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46 积分 2023-10-11 加入
Integrated investigation and experimental validation of PPARG as an oncogenic driver: implications for prognostic assessment and therapeutic targeting in hepatocellular carcinoma
7小时前
已完结
AI-Guided Discoveryof Natural-Product-Inspired Scaffoldsas Dual P-gp/BCRP Inhibitors to Overcome Cancer Multidrug Resistance
5天前
已完结
Discovery andCharacterization of RP04340 : A Highly Potent and OrallyActive Pan-KRAS PROTAC Degrader
14天前
已完结
Two Mechanisms One Molecule: Developing a ‘Truly’ Bifunctional Degrader Targeting Rpn13 and CRBN
18天前
已完结
Berberine derivative B4 alleviates ulcerative colitis via dual HSP60/NLRP3 targeting to restore mitochondrial homeostasis and suppress inflammasome activation
19天前
已完结
Marine Natural Product Chagosendine C Induces Cuproptosis in Colorectal Cancer Cells by Targeting FDX1
20天前
已完结
Alkylsulfonamide-containing quinazoline derivatives as potent and orally bioavailable PI3Ks inhibitors
20天前
已完结
FBXO11 Enhances Colorectal Cancer Progression through TMBIM6 Stabilization: Echinacoside as a Natural Inhibitor
21天前
已完结
Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists
24天前
已完结
Synthesis of α-Aminonitriles via Ammonium-Catalyzed Reactions of Aminoacetonitrile
25天前
已完结
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