Lv4
494 积分 2021-10-09 加入
Minimal Structural Variation of GPR84 Full Agonist Causes Functional Switch to Inverse Agonism
6天前
已完结
Development of a Robust Pd-Catalyzed C–S Coupling for the Synthesis of Janus Kinase Inhibitor GDC-9918
16天前
已完结
Discovery of Selective and Orally Bioavailable Heterobifunctional Degraders of Cyclin-Dependent Kinase 2
1个月前
已完结
Development of a Second-Generation Stereoselective Manufacturing Process for a Key N -Hydroxyamidine Intermediate of GDC-6599 Enabled by Data Science and Mechanistic Understanding
1个月前
已完结
A Bioorthogonally Cleavable N -Oxide Linker for Prodrug Design: Elucidating the Structure-Cyclization Kinetics Relationships for Controlled Drug Release
1个月前
已完结
Engineering a Keto-Reductase for the Mass-Efficient Synthesis of a Key Building Block, Trans -Ethyl (3-Hydroxycyclobutyl)Acetate
1个月前
已完结
Process Development of the RIPK1 Inhibitor Oditrasertib Part 1: Continuous Synthesis of the Pyridine Core
1个月前
已完结
Development of a Scalable Synthesis for the Spirocyclic Benzoxepane–Pyridine Core of FXR Agonist HEC96719
1个月前
已完结
Decagram-Scale Synthesis of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284
1个月前
已完结
Reductive Aminations of Carbonyl Compounds with Borohydride and Borane Reducing Agents
1个月前
已完结