Lv11
68 积分 2025-03-24 加入
The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation
3小时前
待确认
Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3
3小时前
已完结
The E3 ubiquitin ligase NEDD4 negatively regulates HER3/ErbB3 level and signaling
3小时前
已完结
HER3-targeted therapy: the mechanism of drug resistance and the development of anticancer drugs
3小时前
已完结
SIRPα sequesters SHP-2 to promote IL-4 and IL-13 signaling and the alternative activation of macrophages
1个月前
已完结
Reprogramming of TAMs via the STAT3/CD47-SIRPα axis promotes acquired resistance to EGFR-TKIs in lung cancer
1个月前
已完结
ADC target profiling in NSCLC: Generalizable AI separates TROP-2 and cMET phenotypes
1个月前
已完结
Anti-GD2 and Anti-CD47 Are Synergistic and Promote Tumor Eradication
1个月前
已关闭
Nrdp1-mediated ErbB3 degradation inhibits glioma cell migration and invasion by reducing cytoplasmic localization of p27(Kip1)
1个月前
已完结
Clinical Significance of MTAP Deletions and their Overlap with Concurrent Oncogenic Driver Alterations Including EGFR in Non-Small Cell Lung Cancer
6个月前
已完结
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