Lv4
486 积分 2025-03-24 加入
Now with oligos: antibody–oligonucleotide conjugates are the new drug modality to watch
2小时前
已完结
A Drug-Drug Interaction Study Evaluating the Effect of Givosiran, a Small Interfering Ribonucleic Acid, on Cytochrome P450 Activity in the Liver
19天前
已完结
Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial
19天前
已完结
Nonclinical Pharmacokinetics and Absorption, Distribution, Metabolism, and Excretion of Givosiran, the First Approved N-Acetylgalactosamine-Conjugated RNA Interference Therapeutic
19天前
已完结
RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
19天前
已完结
Design and Discovery of a Potent and Selective Inhibitor of Integrin αvβ1
30天前
已完结
Artificial intelligence in the development of small nucleic acid therapeutics: toward smarter and safer medicines
1个月前
已完结
Small-Molecule Ligands Targeting Lysosome-Shuttling Receptors and the Emerging Landscape of Lysosome-Targeting Chimeras
1个月前
已完结
Immunogenicity Risk Assessment for Nucleic Acid Therapeutics: A Comprehensive Evaluation for ASO, siRNA, and Nonvaccine mRNA/LNP Therapies by the IQ Consortium
1个月前
已完结
Delivering silence: advancements in developing siRNA therapeutics
2个月前
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