Lv4
744 积分 2025-03-24 加入
Pharmacokinetics and Pharmacodynamics of GalNAc-Conjugated siRNAs
1天前
已完结
Chemical Modification Strategies for Therapeutic Oligonucleotides: Mechanism Compatibility, Design Trade-Offs, and Translational Barriers
2天前
已完结
Exploring Clearance Pathways for GalNAc-siRNAs: Insights into Intracellular Kinetics and Therapeutic Implications
2天前
已完结
RNA interference in the era of nucleic acid therapeutics
2天前
已完结
Improving the potency prediction for chemically modified siRNAs through insights from molecular modeling of individual sequence positions
2天前
已完结
Acyclic serinol nucleic acid modification of siRNAs overcomes seed region mediated off-target effects while maintaining potency
2天前
已完结
Immunogenicity Assessment for siRNA Therapeutics: A Risk-Based Proposal for Event-Driven Testing
2天前
已完结
CMsiRNAdb: a database of chemically modified SiRNA silencing efficiency for nucleic acid drug design
3天前
已完结
The Computational Journey of siRNA Silencing Efficiency: Resources, Methods, and Future Directions
3天前
已完结
UniPert-G2CP bridges genetic and chemical screens from molecular representation to phenotype modeling
3天前
已完结
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