Lv1
50 积分 2024-07-05 加入
Targeting cancer with small molecule pan-KRAS degraders
6小时前
待确认
Design and synthesis of 4-amino-2′,4′-dihydroxyindanone derivatives as potent inhibitors of tyrosinase and melanin biosynthesis in human melanoma cells
1个月前
已完结
Novel Inhibitor of Glutamate-Cysteine Ligase Catalytic Subunit against Tribolium castaneum: High-Throughout Virtual Screening, Molecular Docking and Dynamics Simulation, and Bioassay
2个月前
已完结
Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3)
2个月前
已完结
Identification of a small-molecule Tim-3 inhibitor to potentiate T cell–mediated antitumor immunotherapy in preclinical mouse models
2个月前
已完结
Design, Synthesis, and Biological Evaluation of Novel Orally Available Covalent CDK12/13 Dual Inhibitors for the Treatment of Tumors
2个月前
已完结
Benchmarking Methods for PROTAC Ternary Complex Structure Prediction
2个月前
已完结
PocketFlow is a data-and-knowledge-driven structure-based molecular generative model
3个月前
已完结
Discovery of Covalent MLKL PROTAC Degraders via Optimization of a Theophylline Derivative Ligand for Treating Necroptosis
4个月前
已完结
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
4个月前
已完结
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