Lv41
730 积分 2023-01-24 加入
Nonsense-Mediated RNA Decay is a Targetable Vulnerability in Splicing Factor Mutant Myeloid Neoplasms by Enhancing R-loop Accumulation and DNA Damage
1个月前
已完结
Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
1个月前
已完结
Targeting ABCD1 inhibits peroxisomal fatty acid oxidation to selectively eliminate acute myeloid leukemia cells
1个月前
已关闭
Site-specific methylation of SRSF2 P95H by SETD2 inhibits MDSC-mediated proinflammatory niche formation in mouse models of myelodysplastic syndrome
3个月前
已完结
Bispecific killer cell engager-secreting CAR-T cells redirect natural killer specificity to enhance antitumour responses
4个月前
已完结
Cellular senescence as a possible link between prostate diseases of the ageing male
6个月前
已完结
Reprogramming the GRHL2−CDK19 axis by gene therapy alleviates prostate aging
6个月前
已完结
A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
11个月前
已完结
Metabolic reprogramming by PRDM16 drives cytarabine resistance in acute myeloid leukemia
1年前
已完结
A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma
1年前
已完结
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