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168 积分 2026-03-03 加入
Is seltorexant, an orexin-2 receptor antagonist, showing promise in insomnia?
1个月前
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Unveiling the binding mechanism of orexin 2 receptor antagonists with computational chemistry
1个月前
已完结
Orexin Receptor Antagonists: Historical Perspectives and Future Opportunities
1个月前
已完结
Efficacy and safety of vornorexant in Japanese patients with insomnia: a randomized, placebo-controlled phase 3 pivotal study
1个月前
已完结
Discovery of IDOR-1117-1680, a dual orexin receptor antagonist with fast onset and short duration of action for the treatment of insomnia
1个月前
已完结
Safety and efficacy of daridorexant in patients with insomnia disorder: results from two multicentre, randomised, double-blind, placebo-controlled, phase 3 trials
2个月前
已完结
Discovery, synthesis and SAR of 3-aryl pyrazolidines, novel dual orexin receptor antagonists for the treatment of sleep disorders
2个月前
已完结
Epidemiology of Insomnia
2个月前
已完结
Identification of a Novel Series of Orexin Receptor Antagonists with a Distinct Effect on Sleep Architecture for the Treatment of Insomnia
2个月前
已完结
Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia
2个月前
已关闭