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madison
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180 积分
2022-01-11 加入
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Current progress and novel strategies that target CDK12 for drug discovery
2天前
已完结
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers
5天前
已完结
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase
5天前
已完结
Quantitative measurement of PROTAC intracellular accumulation
7天前
已完结
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7
7天前
已完结
Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization
7天前
已完结
A High-Throughput Method to Prioritize PROTAC Intracellular Target Engagement and Cell Permeability Using NanoBRET
7天前
已完结
Monitoring PROTAC interactions in biochemical assays using Lumit immunoassays
7天前
已完结
Kinetic Detection of E3:PROTAC:Target Ternary Complexes Using NanoBRET Technology in Live Cells
7天前
已完结
Targeting Her2-insYVMA with Covalent Inhibitors—A Focused Compound Screening and Structure-Based Design Approach
8天前
已完结
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