Lv6
2760 积分 2023-11-06 加入
Discovery of Oxazole Byproduct Formation in the Modified Dakin–West Reaction and Efficient Synthesis of Diastereomeric α-Ketoamide Cysteine Protease Inhibitors
18小时前
已完结
Development of a Manufacturing Process for a Key (S)-5-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1H-indole Intermediate for Orforglipron. Part I. Selection of an Evans Auxiliary-Assisted Asymmetric 1,4-Addition Route
2天前
已完结
SDMA (Synhydrid, Red-Al, Vitride): A Chemoselective and Safe Solution for Reduction Reactions
2天前
已完结
An efficient Mn-catalyzed reductive carbonylation of aryl iodides to aryl aldehydes and their benzimidazole and benzoxazoles
16天前
已完结
Polymorph and Salt/Cocrystal Screening to Identify a Suitable Physical Form for an LPAR1 Antagonist, GS-2278
21天前
已完结
Overcoming Scale-Dependent Impurity Escalation in Epalrestat Synthesis: Identification, Mechanistic Elucidation, and Robust Process Control
21天前
已完结
Scalable Synthesis of Lunresertib, a Selective PKMYT1 Inhibitor
21天前
已完结
Accurate and Scalable Prediction of a Fast and Highly Exothermic Nonlinear Reaction System: Reaction Development Using Coupled Simulation of a Mechanism-Oriented Kinetic Model and a Customized Heat Removal Model
21天前
已完结
Selective 1,2‐Hydroarylation(Alkenylation) of gem‐Difluoroalkenes to Access (−CF2H) Motifs
30天前
已完结
Free Piperazic Acid as a Precursor to Nonribosomal Peptides
1个月前
已完结
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