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16 积分 2025-01-09 加入
Structural basis for DCAF2 as a novel E3 ligase for PROTAC-mediated targeted protein degradation
26天前
已完结
Chemical Proteomics Identifies RBBP7 as a New E3 Ligase Supporting Targeted Protein Degradation
26天前
已完结
A Scalable, Direct‐to‐Biology Platform for Accelerated Discovery of Cereblon‐Based Molecular Glue Degraders
1个月前
已完结
A covalent gambit: An irreversible inhibitor to checkmate drug resistance in tuberculosis
1个月前
已关闭
AMPKα2 attenuates doxorubicin induced ferroptosis by promoting NCOA4 degradation in triple negative breast cancer
1个月前
已完结
Lactylation: The metabolic accomplice shaping cancer's response to radiotherapy and immunotherapy
1个月前
已完结
Structure-guided design of 7-azaindole DNMT1 inhibitors active against hypomethylating agent-resistant acute myeloid leukemia
2个月前
已完结
TOM20-driven E3 ligase recruitment regulates mitochondrial dynamics through PLD6
2个月前
已完结
Identification of an allosteric site on the E3 ligase adapter cereblon
3个月前
已完结
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