Lv11
70 积分 2025-08-03 加入
Preclinical translational physiologically based pharmacokinetic modeling for predicting human pharmacokinetics of proteolysis targeting chimeras: Case studies of vepdegestrant (ARV-471) and bavdegalutamide (ARV-110)
10小时前
已完结
Trastuzumab Rezetecan in Human Epidermal Growth Factor Receptor 2–Expressing Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer: A Multicenter, Open-Label, Phase I Trial
2个月前
已完结
Development of a generic physiologically based pharmacokinetic model to predict clinical pharmacokinetics and assess drug-drug interaction risks for vcMMAE-based antibody-drug conjugates
2个月前
已完结
HRA00129-C004, a Novel c-Met Antibody–Drug Conjugate, Exerts Encouraging Antitumor Activities and Favorable Safety Profiles
2个月前
已完结
Re-Evaluating Antibody–Drug Conjugate Linker Stability: Assessment, Interpretation, and Clinical Translation
2个月前
已完结
Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody–drug conjugates
2个月前
已完结
〈1503〉 Quality Attributes of Synthetic Peptide Drug Substances
4个月前
已关闭
Oligopeptide Regulatory Affairs and Challenges
4个月前
已关闭
Non-Regulated LC–MS/MS Bioanalysis in Support of Early Drug Development: A Novartis Perspective
6个月前
已完结
Antibody-drug conjugates: Current challenges and innovative solutions for precision cancer therapy
8个月前
已完结
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