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70 积分 2025-05-27 加入
Discovery of Pyrazolo[1,5,4-de]quinoxalin-2(3H)-one Derivatives as Highly Potent and Selective PARP1 Inhibitors
9小时前
已完结
WRN as a Novel Target of Synthetic Lethality: Current Advances and Future Perspectives
1个月前
已完结
Synthesis and pharmacological evaluation of glycine amide derivatives as novel vascular adhesion protein-1 inhibitors without CYP3A4 and CYP2C19 inhibition
1个月前
已完结
Design and synthesis of novel substituted naphthyridines as potential c-Met kinase inhibitors based on MK-2461
2个月前
已完结
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
2个月前
已关闭
PROTAC targeted protein degraders: the past is prologue
2个月前
已完结
E3 ligase ligand chemistries: from building blocks to protein degraders
2个月前
已完结
optimization of potent ligands for the E3 ligase DCAF15 and evaluation of their use in heterobifunctional degraders
2个月前
已完结
Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition
2个月前
已完结
Discovery of Edecesertib (GS-5718): A Potent, Selective Inhibitor of IRAK4
3个月前
已完结
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