Lv3
390 积分 2025-04-08 加入
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
5天前
已完结
WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer
6天前
已完结
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
8天前
已完结
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306
8天前
已完结
Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer
9天前
已完结
β-catenin inhibitor ICG-001 suppress cell cycle progression and induce autophagy in endometrial cancer cells
11天前
已完结
Betting on β-catenin inhibitors in oncology
12天前
已完结
C-Arg9-APCR3-VHL promotes β-catenin degradation via the VHL-mediated ubiquitin–proteasome system in APC-mutant colorectal cancer
16天前
已完结
Potent salinomycin C20-O-alkyl oxime derivative SAL-98 efficiently inhibits tumor growth and metastasis by affecting Wnt/β-catenin signal pathway
16天前
已关闭
Discovery of Novel 3-Phenylpiperidine Derivatives Targeting the β-Catenin/B-Cell Lymphoma 9 Interaction as a Single Agent and in Combination with the Anti-PD-1 Antibody for the Treatment of Colorectal Cancer
17天前
已完结