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40 积分 2025-11-14 加入
Impact of stressors in the aviation environment on xenobiotic dosimetry in humans: physiologically based prediction of the effect of barometric pressure or altitude
28天前
已完结
Physiologically based pharmacokinetic modeling for confirming the role of CYP3A1/2 and P‐glycoprotein in detoxification mechanism between glycyrrhizic acid and aconitine in rats
29天前
已完结
Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug–Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models
1个月前
已完结
Evaluating Lean Liver Volume as a Potential Scaler for In Vitro-In Vivo Extrapolation of Drug Clearance in Obesity Using the Model Drug Antipyrine
1个月前
已关闭
The Effect of Retroconversion Metabolism of N-oxide Metabolites by Intestinal Microfloraon Piperaquine Elimination in Mice, as well as in Humans Predicted Using aPBPK Model
1个月前
已完结
Identification of the Human Cytochromes P450 Responsible for in Vitro Formation of R- and S-Norfluoxetine
1个月前
已关闭
Prediction of Fluoxetine and Norfluoxetine Pharmacokinetic Profiles Using Physiologically Based Pharmacokinetic Modeling
1个月前
已完结
Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500�m)
2个月前
已完结
Downregulation of CYP1A2, CYP2B6, and CYP3A4 in Human Hepatocytes by Prolyl Hydroxylase Domain 2 Inhibitors via Hypoxia-Inducible Factor-α Stabilization
2个月前
已完结
Acute hypoxia and cytochrome P450–mediated hepatic drug metabolism in humans
2个月前
已完结
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