Lv1
5 积分 2022-01-26 加入
Targeting cancer with small molecule pan-KRAS degraders
6天前
已完结
A Peptide-Based PROTAC Degrader of BRCA2 Sensitizes Metastatic Castration-Resistant Prostate Cancer to PARP Inhibition
24天前
已完结
USP13 ameliorates diabetic cardiomyopathy via deubiquitinating NLRP3 and inhibiting pyroptosis in cardiomyocytes
1个月前
已完结
Cancer interception with KRAS inhibitors in preclinical models of pancreatic ductal adenocarcinoma
1个月前
已完结
Establishment of a quantitative ELISA capable of determining peptide – MHC class I interaction
1个月前
已完结
AGPAT4 targeted covalent inhibitor potentiates targeted therapy to overcome cancer cell plasticity in hepatocellular carcinoma mouse models
2个月前
已完结
A first-in-class small-molecule inhibitor targeting AVIL exhibits safety and antitumor efficacy in preclinical models of glioblastoma
2个月前
已完结
USP5 inhibition enables potential therapy for t(8;21) AML through ubiquitin-mediated AML1-ETO degradation in patient-derived xenografts
3个月前
已完结
Targeted protein degradation in the transmembrane and extracellular space
4个月前
已完结
JMJD6 Rewires ATF4-Dependent Glutathione Metabolism to Confer Ferroptosis Resistance in SPOP-Mutated Prostate Cancer
4个月前
已完结