Lv64
2160 积分 2022-06-18 加入
Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes
1个月前
已完结
RIG-I-targeted immunotherapy synergizes with immune checkpoint inhibition in a hepatocellular carcinoma model
1个月前
已完结
Discovery of small-molecule ATR inhibitors for potential cancer treatment: a patent review from 2014 to present
1个月前
已完结
A medicinal chemistry perspective on ATR: Current status and future directions
1个月前
已完结
The Trop-2-targeting antibody drug conjugate DB-1305 has higher antitumor activity and a potentially better safety profile compared with DS-1062
3个月前
已完结
DB-1303, a HER2-targeting ADC with a novel DNA topoisomerase I inhibitor, demonstrates a promising safety profile and anti-tumor efficacy with differentiation from DS-8201a
3个月前
已完结
Re-Evaluating Antibody–Drug Conjugate Linker Stability: Assessment, Interpretation, and Clinical Translation
3个月前
已完结
Loss of payload sensitivity and other mechanisms of resistance to T-DXd in HER2-mutant NSCLC: implications for subsequent responsiveness to HER2 TKIs
6个月前
已完结
Targeting the tumour cell surface in advanced prostate cancer
9个月前
已完结
Contactin-4 suppresses antitumor T cell responses by engaging amyloid precursor protein
9个月前
已完结
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