Lv63
1810 积分 2022-09-27 加入
Targeting chromosomally unstable tumors with a selective KIF18A inhibitor
21天前
已完结
Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement
22天前
已完结
Structure-Guided Discovery of Novel N4-(Substituted Thiazol-2-yl)-N2-(4-Substituted phenyl)pyrimidine-2,4-Diamines as Potent CDK2 and CDK9 Dual Inhibitors with High Oral Bioavailability
22天前
已完结
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
22天前
已完结
Cheminformatic Analysis of Core-Atom Transformations in Pharmaceutically Relevant Heteroaromatics
1个月前
已完结
Altering distribution profile of palbociclib by its prodrugs
1个月前
已完结
Palbociclib, ribociclib, and abemaciclib: potent and selective CDK4/6 inhibitors for the treatment of breast cancer
1个月前
已完结
Elucidating Binding Selectivity in Cyclin-Dependent Kinases (CDKs) 4, 6, and 9: Development of Highly Potent and Selective CDK4/9 Inhibitors
1个月前
已完结
Cellular Uptake and Efflux of Palbociclib In Vitro in Single Cell and Spheroid Models
2个月前
已完结
Targeting autophagy plus high-dose CDK4/6 inhibitors in advanced HR+HER2− breast cancer: A phase 1b/2 trial
2个月前
已完结
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