Lv4
418 积分 2024-07-16 加入
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment
14天前
已完结
Developing SHP2-based combination therapy for KRAS-amplified cancer
1个月前
已完结
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
1个月前
已完结
Cotargeting signaling pathways driving survival and cell cycle circumvents resistance to Kit inhibitors in leukemia
1个月前
已完结
Combination of 5-fluorouracil and 2-morphilino-8-phenyl-4H-chromen-4-one may inhibit liver cancer stem cell activity
1个月前
已完结
Critical individual roles of the BCR and FGFR1 kinase domains in BCR‐FGFR1‐driven stem cell leukemia/lymphoma syndrome
1个月前
已完结
SHP2 Inhibition Influences Therapeutic Response to Tepotinib in Tumors with MET Alterations
1个月前
已完结
SHP2 Targets ITK Downstream of PD-1 to Inhibit T Cell Function
1个月前
已完结
TLR7/8 Agonist and SHP2 Inhibitor Loaded Nanoparticle Enhances Macrophage Immunotherapy Efficacy
1个月前
已完结
SHP2 Inhibition Enhances the Effects of Tyrosine Kinase Inhibitors in Preclinical Models of Treatment-naïve ALK-, ROS1- , or EGFR -altered Non–small Cell Lung Cancer
1个月前
已完结