Lv4
584 积分 2024-07-16 加入
Rational design of next-generation PDK1 modulators: Addressing selectivity and resistance through molecular insights — A medicinal chemistry perspective
20天前
已完结
Photothermally Enhanced Cascaded Nanozyme‐Functionalized Black Phosphorus Nanosheets for Targeted Treatment of Infected Diabetic Wounds
26天前
已完结
Light-responsive Au@Zn-TCPP nanozyme functionalized with cell-penetrating peptide and antisense oligonucleotide for sensing living bacteria and synergistic therapy of diabetic wounds
26天前
已完结
Discovery of FYJ-195 as a Highly Potent FLT3 Inhibitor against Multiple Acquired Resistance Mutations in Acute Myeloid Leukemia
1个月前
已完结
Design and optimization of selective and potent CDK9 inhibitors with flavonoid scaffold for the treatment of acute myeloid leukemia
1个月前
已完结
Machine learning-aided design, synthesis and biological evaluation of novel 4-(imidazo[1,2-a]pyridine-3‑carbonyl) phenyl urea derivatives as potent FLT3 inhibitors
1个月前
已完结
Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations
1个月前
已完结
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
1个月前
已完结
Design, synthesis and biological evaluation of 8-phenylquinazolin-2-amine derivatives as FLT3 covalent inhibitors targeting cysteine 828 in the ATP pocket
1个月前
已完结
Exploring the allosteric effect of SHP2 Tyr62 phosphorylation on the emergence of acquired resistance to allosteric inhibitor SHP099
2个月前
已完结
皖公网安备34019202002308
