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美味云宝
Lv3
205 积分
2023-10-29 加入
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Degrader-antibody conjugates
11天前
已完结
The Parkinson’s Disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress
2个月前
已完结
Discovery of HZ-L105, a Next Generation of Bcl-2 Inhibitor, Overcomes Bcl-2 Mutation and Exhibits Superior Antitumor Activity
3个月前
已关闭
Optimization of Selectivity and Pharmacokinetic Properties of Salt-Inducible Kinase Inhibitors that Led to the Discovery of Pan-SIK Inhibitor GLPG3312
4个月前
已完结
AACR-NCI-EORTC - 34th International Symposium on Molecular Targets and Cancer Therapeutics. Barcelona - October 26-28, 2022
6个月前
已完结
ASP3082, a First-in-class novel KRAS G12D degrader, exhibits remarkable anti-tumor activity in KRAS G12D mutated cancer models
6个月前
已完结
Drugging RAS: Moving Beyond KRASG12C
6个月前
已完结
Discovery of highly potent and selective KRASG12C degraders by VHL-recruiting PROTACs for the treatment of tumors with KRASG12C-Mutation
6个月前
已完结
Efficient targeted oncogenic KRASG12C degradation via first reversible-covalent PROTAC
6个月前
已完结
Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activity
6个月前
已完结
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