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55 积分 2021-04-15 加入
Tertiary Alcohol: Reaping the Benefits but Minimizing the Drawbacks of Hydroxy Groups in Drug Discovery
18天前
已完结
N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
21天前
已完结
2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands
21天前
已完结
Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds
21天前
已完结
Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948
27天前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
1个月前
已完结
Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide
1个月前
已完结
Structure-Based Discovery of a Highly Selective, Oral Polo-Like Kinase 1 Inhibitor with Potent Antileukemic Activity
2个月前
已完结
Targeting c-MYC and gain-of-function p53 through inhibition or degradation of the kinase LZK suppresses the growth of HNSCC tumors
2个月前
已完结
Sulfilimines from a Medicinal Chemist’s Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery
3个月前
已完结
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