Lv31
253 积分 2021-04-15 加入
Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-κB Ligand (RANKL)—Receptor Activator of Nuclear Factor-κB (RANK) Protein–Protein Interaction by Structure-Based Virtual Screening and Hit Optimization
1小时前
已完结
Synthesis and Antiosteoporotic Characterization of Diselenyl Maleimides: Discovery of a Potent Agent for the Treatment of Osteoporosis by Targeting RANKL
1小时前
已完结
Identification of a RANKL/TNF-α Dual-Inhibitor as a Potential Disease-Modifying Agent for the Treatment of Knee Osteoarthritis
1小时前
已完结
Design, Synthesis, and Biological Evaluation of Heterocycle-Fused Celastrol Derivatives as Potent Antiosteoporosis Agents by Blocking RANKL-Induced Activation of the NF-κB and MAPK Signaling Pathways
5天前
已完结
On the Metabolic Stability of Fluorinated Small Molecules; A Physical Organic Chemistry Perspective
12天前
已完结
Identification of Potential Megalin/Cubilin Substrates Using Extensive Proteomics Quantification from Kidney Megalin-Knockdown Mice
12天前
已完结
Design, Optimization, and Biological Evaluation of First-in-Class Triple Inhibitors of SGLT1, SGLT2, and DPP4 for Type 2 Diabetes Mellitus
1个月前
已完结
Structure-Based Development of a Novel Macrocyclic Peptide to Disrupt the Lumican–Collagen I Interaction in Liver Fibrosis
2个月前
已完结
Discovery of Non-benzoazacyclic V 2 R Antagonists for the Treatment of Autosomal Dominant Polycystic Kidney Disease
2个月前
已完结
Identification of key immune genes of drug-induced liver injury induced by tolvaptan based on bioinformatics
2个月前
已完结
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