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183 积分 2021-04-15 加入
Discovery of Potent and Selective MNK Kinase Inhibitors for the Treatment of Leukemia
2天前
已完结
Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eFT508) Combined With Paclitaxel in Patients With Refractory Metastatic Breast Cancer
2天前
已完结
Structural Transformation of a BRAF Inhibitor into a Selective PKR Inhibitor
8天前
已完结
Structural Transformation of a BRAF Inhibitor into a Selective PKR Inhibitor
8天前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
18天前
已完结
A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner
18天前
已完结
Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors
22天前
已完结
P0837 Sustained symptomatic relief and disease clearance through 50 weeks of treatment with tulisokibart in participants with moderately to severely active ulcerative colitis in the phase 2 ARTEMIS-UC study
24天前
已关闭
Discovery of HW201877: A Highly Potent and Orally Bioavailable Inhibitor of 15-Prostaglandin Dehydrogenase to Potentiate Tissue Repair and Regeneration
1个月前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
2个月前
已完结
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