Lv3
223 积分 2021-04-15 加入
Discovery of HW201877: A Highly Potent and Orally Bioavailable Inhibitor of 15-Prostaglandin Dehydrogenase to Potentiate Tissue Repair and Regeneration
2天前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
25天前
已完结
Molecular glue-based RAS–MAPK targeting
25天前
已完结
First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients
1个月前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
1个月前
已完结
Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2
1个月前
已完结
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
1个月前
已完结
C5a Receptor (CD88) Blockade Protects against MPO-ANCA GN
2个月前
已完结
Structure of Designer Antibody-like Peptides Binding to the Human C5a with Potential to Modulate the C5a Receptor Signaling
2个月前
已完结
Discovery and Characterization of a New Class of C5aR1 Antagonists Showing In Vivo Activity
2个月前
已完结
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