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14 积分 2025-07-21 加入
Advances in covalent drug discovery
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Small molecules, big targets: drug discovery faces the protein–protein interaction challenge
7小时前
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Discovery of a selective inhibitor of doublecortin like kinase 1
7小时前
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Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes
7小时前
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A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity
7小时前
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The ins and outs of selective kinase inhibitor development
8小时前
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Targeting cancer with small molecule kinase inhibitors
8小时前
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Kinase drug discovery 20 years after imatinib: progress and future directions
8小时前
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Kinase inhibitors: the road ahead
8小时前
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Surrogate End Points for Overall Survival in Neoadjuvant Randomized Clinical Trials for Early Breast Cancer
24天前
已完结