Lv11
10 积分 2025-09-24 加入
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
4小时前
待确认
A Prodrug Strategy to Conditionally Trap Therapeutic Payloads for Improved Tumor Retention
25天前
已完结
Charge-reversal proteolysis polymers enable tissue-specific STING degradation in rheumatoid arthritis
4个月前
已完结
Design and screening of a chimeric survivin-specific nanobody and its anticancer activities in vitro
4个月前
已完结
A Genome-Wide CRISPR Screen Identifies Sortilin as the Receptor Responsible for Galectin-1 Lysosomal Trafficking
6个月前
已完结
A molecular glue halts RAS–MAPK signaling
6个月前
已完结
Tumor PD-L1 induces β2m ubiquitylation and degradation for cancer cell immune evasion
7个月前
已完结
A cytokine receptor-targeting chimera (kineTAC) toolbox for expanding extracellular targeted protein degradation
8个月前
已完结
Unveiling the molecular and immunological drivers of antibody–drug conjugates in cancer treatment
8个月前
已完结
Engineering TME-gated inducible CAR-T cell therapy for solid tumors
9个月前
已完结
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