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30 积分 2025-09-22 加入
Potent and Orally Bioavailable BCL6 PROTAC TM Degraders Demonstrate Efficacy in Pre-Clinical Models of Diffuse Large B-Cell Lymphoma (DLBCL)
17天前
已完结
GSK137, a potent small-molecule BCL6 inhibitor with in vivo activity, suppresses antibody responses in mice
17天前
已完结
Overview of epigenetic degraders based on PROTAC, molecular glue, and hydrophobic tagging technologies
17天前
已完结
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4
17天前
已完结
Relocalizing transcriptional kinases to activate apoptosis
19天前
已完结
BET bromodomain inhibitors
20天前
已完结
Identification of Benzofuro[2,3-b]pyridine Pseudonatural Product as a Novel Class of Ferritinophagy Inhibitors that Potently Suppress Ferroptosis
26天前
已完结
Identification of Benzofuro[2,3b]pyridine Pseudonatural Product as a Novel Class of Ferritinophagy Inhibitors that Potently Suppress Ferroptosis
26天前
已关闭
The BET protein inhibitor apabetalone (RVX-208) restores angiogenic response in type 1 and type 2 diabetes by transcriptional regulation of thrombospondin-1
1个月前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
3个月前
已完结