Lv6
2970 积分 2023-03-27 加入
Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity
9天前
已完结
Discovery of SPH5030, a Selective, Potent, and Irreversible Tyrosine Kinase Inhibitor for HER2-Amplified and HER2-Mutant Cancer Treatment
10天前
已完结
Discovery of DCAF16 Binders for Targeted Protein Degradation
15天前
已完结
Rational Design of Dual Degraders by Incorporating Molecular Glue Structural Features into PROTAC Degraders
15天前
已完结
Development of potent and selective CK1α Molecular Glue Degraders
15天前
已完结
Targeting QPCTL: An Emerging Therapeutic Opportunity
24天前
已完结
UNC9426, a Potent and Orally Bioavailable TYRO3-Specific Inhibitor
1个月前
已完结
Discovery of Highly Potent AKR1C3 Inhibitors Treating Sorafenib-Resistant Hepatocellular Carcinoma
1个月前
已完结
Discovery of Novel TYRO3/MERTK Dual Inhibitors
1个月前
已完结
Ubiquitin-Specific Protease 7 (USP7) as a Promising Therapeutic Target for Drug Discovery: From Mechanisms to Therapies
1个月前
已完结
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