Lv7
4990 积分 2023-03-27 加入
Strategic Use of Benzylic Alcohols Reveals Cryptic Hydrogen-Bonding Interactions: Discovery of HBC-12551 as a Potent Noncovalent Bruton’s Tyrosine Kinase Inhibitor
2天前
已完结
Discovery of CZL-149: A Novel, Highly Potent, and Orally Bioavailable Dual Inhibitor Targeting BET and p300/CBP Bromodomains with Strong Antitumor Efficacy
6天前
已完结
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists
6天前
已完结
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors
10天前
已完结
ACLY inhibition promotes tumour immunity and suppresses liver cancer
18天前
已完结
Targeting cancer with small molecule pan-KRAS degraders
23天前
已完结
Inavolisib-Based Therapy in PIK3CA -Mutated Advanced Breast Cancer
29天前
已完结
From KRAS G12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design
1个月前
已完结
Optimization of Covalent 6-Cyanoquinazoline KRAS G12C Inhibitors for the Treatment of Solid Tumors
1个月前
已完结
Optimization of α-Fluoro, β-Heteroaryl Acrylamide Warheads for KRAS G12C Active-State Inhibition
1个月前
已完结
皖公网安备34019202002308
