Lv11
48 积分 2022-12-05 加入
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
51分钟前
已完结
The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation
7天前
已完结
Small molecules that targeting p53 Y220C protein: mechanisms, structures, and clinical advances in anti-tumor therapy
12天前
已完结
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity
19天前
已完结
THERAPEUTIC EFFICACY OF A NOVEL ORAL NRF2 ACTIVATOR IN A MURINE ULCERATIVE COLITIS MODEL
19天前
已关闭
Structure-based design of Sec61 translocon targeting prodrugs minimize off-target toxicity
20天前
已完结
A common mechanism of Sec61 translocon inhibition by small molecules
20天前
已完结
A brain-penetrant TRPML1 agonist enhances autophagy–lysosomal function and mitigates pathology in aged models of Parkinson’s and Alzheimer’s diseases
26天前
已完结
A Proof-of-Concept Study Evaluating the Phosphodiesterase 10A Inhibitor PF-02545920 in the Adjunctive Treatment of Suboptimally Controlled Symptoms of Schizophrenia
2个月前
已完结
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