Lv1
60 积分 2022-12-05 加入
Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression
9天前
已完结
Molecular Glues Recruiting RNF213 As an E3 Ligase for Targeted Protein Degradation: A Minimal Dibromoacetamide Warhead As a Recruitment Ligand
11天前
已完结
TNFR2-targeting biologics: Molecular mode of action, possible applications, and future developments
19天前
已完结
Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases
19天前
已完结
TNF and TNF receptors as therapeutic targets for rheumatic diseases and beyond
23天前
已完结
A small molecule modulating heterogeneous amyloid-β isoforms improves cognitive and pathological outcomes in acute and 5XFAD Alzheimer's disease models
25天前
已完结
MAINTENANCE EFFICACY OF ORAL INDIGO NATURALIS FOR ULCERATIVE COLITIS: A SINGLE-CENTER, OPEN-LABEL, RANDOMIZED, CONTROLLED STUDY
1个月前
已完结
γ-Secretase modulation inhibits amyloid plaque formation and growth and stimulates plaque regression in amyloid precursor protein/presenilin-1 mice
1个月前
已关闭
Molecular mechanism of substrate recognition and cleavage by human γ-secretase
1个月前
已完结
Phase 1 randomized trial of HS-10353, a novel GABA(A) positive allosteric modulator for treatment of major depressive disorder
1个月前
已完结
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