Lv6
2494 积分 2026-01-21 加入
Incorporation of healthy volunteers data on receptor occupancy into a phase II proof‐of‐concept trial using a Bayesian dynamic borrowing design
15天前
已完结
Discovery of the novel and potent histamine H1 receptor antagonists for treatment of allergic diseases
28天前
已完结
Ligelizumab in adolescents with chronic spontaneous urticaria: Results of a dedicated phase 2b randomized clinical trial supported with pharmacometric analysis
1个月前
已完结
BMA‐Mod: A Bayesian model averaging strategy for determining dose‐response relationships in the presence of model uncertainty
1个月前
已完结
A Bayesian design for finding optimal biological dose with mixed types of responses of toxicity and efficacy
1个月前
已完结
Integrative population pharmacokinetic modeling of two BCMA-targeted and one CD19-targeted CAR-T therapies using full Bayesian inference with a student’s t-based M3 censoring approach for robust handling of outliers and BLQ data
2个月前
已关闭
Enhancing pharmacometric modeling with full Bayesian inference and Student’s t-Based M3 Censoring: A simulated population PK study on robust handling of outliers and censored data
2个月前
已关闭
Develop adult extrapolation to pediatrics and pediatric dose optimization based on the physiological pharmacokinetic model of azithromycin
2个月前
已完结
Safety, pharmacokinetics, and sex hormone suppression of LY01021 versus relugolix: A single- and multiple-dose escalation study
2个月前
已完结
Guidelines for the diagnosis and treatment of refractory chronic spontaneous urticaria in China （2025 edition）
3个月前
已完结
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