Lv1
10 积分 2025-01-08 加入
4-Anilinoquinazoline Derivatives as the First Potent NOD1-RIPK2 Signaling Pathway Inhibitors at the Nanomolar Range
1天前
已完结
CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury
1天前
已完结
Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease
1天前
已完结
Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer
2天前
已完结
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer
3天前
已完结
Vectorized ULK1/2 and VPS34 Inhibitors for Tissue-Selective Autophagy Inhibition in Oncology
3天前
已完结
Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties
3天前
已完结
Discovery of AXL Degraders with Improved Potencies in Triple-Negative Breast Cancer (TNBC) Cells
8天前
已完结
Advances and therapeutic opportunities in visual cycle modulation
14天前
已关闭
Tyrosine kinase inhibitors for acute myeloid leukemia: A step toward disease control?
15天前
已完结