Lv51
850 积分 2024-08-08 加入
From Unmet Medical Need to Drug Candidate: A Translational Therapeutic Development Roadmap Illustrated by Dual-Payload Antibody–Drug Conjugates
13天前
已完结
Recent Advancesin Peptide Linkers for Antibody-DrugConjugates
13天前
已关闭
NEXUS-01, a phase 1 study of LY4052031, an antibody-drug conjugate targeting Nectin-4 in participants with advanced or metastatic urothelial carcinoma or other solid tumors
20天前
已关闭
P-Glycoprotein Recognition of Substrates and Circumvention through Rational Drug Design
28天前
已完结
Antibody-Drug Conjugate Sacituzumab Govitecan Enables a Sequential TOP1/PARP Inhibitor Therapy Strategy in Patients with Breast Cancer
1个月前
已完结
CDK7 Inhibition Synergizes with Topoisomerase I Inhibition in Small Cell Lung Cancer Cells by Inducing Ubiquitin-Mediated Proteolysis of RNA Polymerase II
1个月前
已完结
Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines
1个月前
已完结
Structural basis of nectin-4 recognition by the antibody–drug conjugate 9MW2821
2个月前
已完结
Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides
2个月前
已完结
Discovery of Novel N-Linked Camptothecin Linker-Payloads to Access Antibody-Drug Conjugates with High Target-Mediated In Vivo Efficacy
2个月前
已完结