Lv3
214 积分 2024-12-13 加入
Hydrophobic Tag Degraders Overcome Endocrine-Resistant Breast Cancer by Recruiting HSP27-Mediated E3 Ligase Complex for ERα Proteasomal Degradation
8天前
已完结
E3 Ligase-Ligand Pairing Strategies for Optimized PROTAC Performance
16天前
已完结
*Development of PROTACs targeting estrogen receptor: an emerging technique for combating endocrine resistance*PMC
17天前
已完结
Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a Pan-Degrader ChemMedChem
20天前
已完结
Discovery of Effective Dual PROTAC Degraders with Synergistic Antitumor Activity for Overcoming Tamoxifen-Resistant Breast Cancer
20天前
已完结
A Novel Dual-Targeting PROTAC Overcomes Endocrine Resistance by Engaging Orthosteric and Allosteric Sites of Estrogen Receptor α
20天前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
20天前
已完结
On the Scope of DCAF1‑Recruiting PROTACs Degrading Protein Kinases
22天前
已完结
Discovery of ERD-12310A as an Exceptionally Potent and Orally Efficacious PROTAC Degrader of Estrogen Receptor α (ERα)
2个月前
已完结
Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer
2个月前
已完结
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