Lv12
36 积分 2024-12-13 加入
First-in-Class Quinoline-Dione-Derived PROTACs: Potent Degraders of Cdc25 Phosphatases for Antitumor Therapy
3小时前
已完结
Discovery of Novel Alkynylbenzene Scaffold-Based PTPN2-Selective Degrader PD-305 with Exceptional Potency and In Vivo Efficacy
22小时前
已完结
Targeted Degradation of Prolyl Hydroxylase Domain Enzyme 1 (PHD1) as a Novel Therapeutic Strategy for Acetaminophen-Induced Acute Liver Injury
22小时前
已完结
Exploiting E3 ligases for lung cancer therapy: The promise of DCAF-PROTACs
12天前
已完结
Abstract LB037: A systematic mass spectrometry-based chemoproteomic platform (chomiXdegradeTM) for molecular glue degrade discovery and mechanistic dissection
12天前
已关闭
DCAF16-Based Covalent Degradative Handles for the Modular Design of Degraders
28天前
已完结
DCAF16-Based Covalent Molecular Glues for Targeted Protein Degradation of Histone Deacetylase
28天前
已关闭
Structure-Guided Optimization of DCAF16 Covalent Ligands
28天前
已完结
Cyanoacrylamide Warheads for Reversible Covalent DCAF16 Molecular Glues
28天前
已完结
DCAF16-Targeting Covalent PROTACs for Selective Degradation of SMARCA2/4
28天前
已关闭
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