Lv1
6 积分 2024-12-13 加入
Development of PROTAC degrader probe of CDK4/6 based on DCAF16
22小时前
已完结
Development of PROTAC degrader probe of CDK4/6 based on DCAF16, and PARP DCAF16 degraders
22小时前
已完结
Discovery of KRAS-G12D degraders via exploration of various E3 ligases
2天前
已完结
DCAF16‐Based Covalent Molecular Glues for Targeted Protein Degradation of Histone Deacetylases
2天前
已完结
Structural basis for DCAF2 as a novel E3 ligase for PROTAC-mediated targeted protein degradation
9天前
已完结
Rational Design of Potent and Orally Efficacious PI3Kα/δ Degrader for PIK3CA Mutant Breast Cancer without Hyperglycemic Liability
14天前
已完结
First-in-Class Quinoline-Dione-Derived PROTACs: Potent Degraders of Cdc25 Phosphatases for Antitumor Therapy
14天前
已完结
Discovery of Novel Alkynylbenzene Scaffold-Based PTPN2-Selective Degrader PD-305 with Exceptional Potency and In Vivo Efficacy
15天前
已完结
Targeted Degradation of Prolyl Hydroxylase Domain Enzyme 1 (PHD1) as a Novel Therapeutic Strategy for Acetaminophen-Induced Acute Liver Injury
15天前
已完结
Exploiting E3 ligases for lung cancer therapy: The promise of DCAF-PROTACs
27天前
已完结
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