Lv2
106 积分 2022-09-20 加入
Nivolumab plus chemotherapy versus placebo plus chemotherapy in patients with HER2-negative, untreated, unresectable advanced or recurrent gastric or gastro-oesophageal junction cancer (ATTRACTION-4): a randomised, multicentre, double-blind, placebo-controlled, phase 3 trial
1个月前
已完结
Programmable bacteria synergize with PD-1 blockade to overcome cancer cell–intrinsic immune resistance mechanisms
1个月前
已完结
MSR1+ macrophages passivate antitumor immunity by inducing ITM2A+ CD4T exhaustion differentiation
5个月前
已完结
Alleviated T cell exhaustion and SLC1A3-mediated stroma-remodelling dictate chemoimmunotherapy efficacy in oesophageal squamous cell carcinoma
7个月前
已完结
Biselective remodeling of the melanoma tumor microenvironment prevents metastasis and enhances immune activation in mouse models
8个月前
已完结
Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness-Mediated Bimodal PD-L1/CXCL10 Regulation
10个月前
已完结
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway
10个月前
已完结
Lactylation orchestrates ubiquitin-independent degradation of cGAS and promotes tumor growth
10个月前
已完结
Piezo1 Mediates Glycolysis-Boosted Pancreatic Ductal Adenocarcinoma Chemoresistance within a Biomimetic Three-Dimensional Matrix Stiffness
1年前
已完结