Lv4
688 积分 2022-07-24 加入
Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myeloma
5天前
已完结
Oncometabolite 5-IP7 inhibits inositol 5-phosphatase to license E-cadherin endocytosis
18天前
已完结
Structure-guided design of 7-azaindole DNMT1 inhibitors active against hypomethylating agent–resistant acute myeloid leukemia
26天前
已完结
Targeted degradation of c-Myc through the midnolin–proteasome pathway
2个月前
已完结
MYC in cancer: from undruggable target to clinical trials
2个月前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
2个月前
已完结
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
2个月前
已完结
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS
2个月前
已完结
Targeting cancer with molecular glues
2个月前
已完结
Current advances of small molecule E3 ligands for proteolysis-targeting chimeras design
2个月前
已完结
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