Lv1
20 积分 2025-10-22 加入
Discovery of TQ-3959 as a Potent and Orally Bioavailable BTK PROTAC Degrader Incorporating a Novel Benzisoxazole-Based CRBN Ligand for the Treatment of B-Cell Malignancies
1个月前
已完结
Development of High-Affinity Ligands for Human UBR2
1个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
2个月前
已完结
Copper-Catalyzed Intermolecular Cyclopropanation of Benzofurans and Indoles
2个月前
已完结
Discovery, Optimization, and Biological Evaluation of 2-Cyano-2-(9 H -xanthen-9-ylidene)acetamide Derivatives as ZNF207 Inhibitors for Anti-Glioma Therapy
3个月前
已完结
Application and challenges of nitrogen heterocycles in PROTAC linker
3个月前
已完结
Design, synthesis and biological evaluation of novel quinazolinone derivatives as CRBN E3 ligase modulators
3个月前
已完结
Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis
3个月前
已完结
Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B
5个月前
已完结
Cdc25 Phosphatases: Structure, Specificity, and Mechanism
5个月前
已完结
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