Lv6
2589 积分 2021-01-15 加入
Brain Penetration Optimization and Anti-neuroinflammation Evaluation of Potent 6-Methyl-7-azaindol-3-yl-quinazoline DYRK1A Inhibitors for Alzheimer’s Disease
3天前
已完结
Discovery of Thiochroman Derivatives as Potent, Oral Selective Estrogen Receptor Degraders and Antagonists for the Treatment of Endocrine-Resistant Breast Cancer
15天前
已完结
Discovery and Characterization of PVTX-321 as a Potent and Orally Bioavailable Estrogen Receptor Degrader for ER+/HER2– Breast Cancer
15天前
已完结
Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity
15天前
已完结
The breast cancer drug market
16天前
已完结
Design and Synthesis of a Novel Covalent Dihydropteridinone Derivative as a Highly Potent and Orally Bioavailable PLK1 Inhibitor for the Treatment of Chronic Myeloid Leukemia
1个月前
已完结
Evolving Strategies for Previously Drugged Therapeutic Targets: Medicinal Chemistry Insights from Paradigmatic Cases
1个月前
已完结
Targeting Metallo-β-Lactamases: Discovery of Novel Dihydro-Chromeno Pyrrole (dCPs) Derivatives for Combating Drug-Resistant Infections
1个月前
已完结
Targeted Degradation of Bromodomain-Containing Protein 4 Enabled by Reactive Oxygen Species–Activatable NanoPROTACs as an Efficient Strategy to Reverse Liver Fibrosis in Chronic Liver Injury
1个月前
已完结
Discovery of APH02174 as a Highly Selective and Orally Bioavailable IRAK4 Degrader for the Treatment of Inflammatory Diseases
1个月前
已完结
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