Lv1
30 积分 2024-07-05 加入
Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology
10小时前
待确认
Cathepsin B-Labile Dipeptide Linkers for Lysosomal Release of Doxorubicin from Internalizing Immunoconjugates: Model Studies of Enzymatic Drug Release and Antigen-Specific In Vitro Anticancer Activity
1个月前
已完结
Impact of dipeptide on ADC physicochemical properties and efficacy identifies Ala–Ala as the optimal dipeptide
1个月前
已完结
Dipeptide-based highly potent doxorubicin antibody conjugates
1个月前
已完结
Design and Application of Cereblon-Recruiting Prodegraders
1个月前
已完结
The Methylene Alkoxy Carbamate Self‐Immolative Unit: Utilization for the Targeted Delivery of Alcohol‐Containing Payloads with Antibody–Drug Conjugates
1个月前
已完结
Advanced Pyrrolidine‐Carbamate Self‐Immolative Spacer with Tertiary Amine Handle Induces Superfast Cyclative Drug Release
1个月前
已完结
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
2个月前
已完结
The discovery of a potent PARP1 inhibitor Senaparib
2个月前
已完结
Derivation of AZD5335, a novel FRα-targeted TOP1i-loaded ADC, for the treatment of FRα-expressing cancers
2个月前
已完结
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