Lv4
630 积分 2024-04-24 加入
Synthesis of new indole benzylic alcohols as potential precursors of calixindoles
13天前
已完结
Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases
1个月前
已完结
A Practical Synthesis of l-Valyl-pyrrolidine-(2R)-boronic Acid: Efficient Recycling of the Costly Chiral Auxiliary (+)-Pinanediol
1个月前
已完结
Design of N -Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor
1个月前
已完结
Rational Design to Large-Scale Synthesis: Development of GSK8175 for the Treatment of Hepatitis C Virus Infection
1个月前
已完结
Deep-Learning-Driven Discovery of SN3–1, a Potent NLRP3 Inhibitor with Therapeutic Potential for Inflammatory Diseases
1个月前
已完结
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor
1个月前
已完结
Discovery of Novel NLRP3 Inflammasome Inhibitors Composed of an Oxazole Scaffold Bearing an Acylsulfamide
1个月前
已完结
Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity
1个月前
已完结
Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 Inhibitors
1个月前
已完结
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