Lv11
34 积分 2024-09-20 加入
FGFR-targeted therapeutics: clinical activity, mechanisms of resistance and new directions
1小时前
已完结
Reduction of NLRP3 inflammasome-mediated inflammation in a novel inducible NEK7 knockout mouse model
1个月前
已完结
Design, Synthesis, and Biological Evaluation of Heterocycle-Fused Celastrol Derivatives as Potent Antiosteoporosis Agents by Blocking RANKL-Induced Activation of the NF-κB and MAPK Signaling Pathways
1个月前
已完结
De Novo Discovery of a Macrocyclic Peptide Antagonist of Interleukin-11 with Antirenal Fibrotic Efficacy
1个月前
已完结
Ofirnoflast: A First-in-Class NEK7-Targeted Inhibitor of the NLRP3 Inflammasome
1个月前
已完结
NEK7 phosphorylation amplifies NLRP3 inflammasome activation downstream of potassium efflux and gasdermin D
2个月前
已完结
Knockdown of NEK7 alleviates anterior cruciate ligament transection osteoarthritis (ACLT)-induced knee osteoarthritis in mice via inhibiting NLRP3 activation
2个月前
已完结
Reduction of polycystic kidney and liver volumes in a patient with tolvaptan-resistant autosomal dominant polycystic kidney disease and acromegaly during lanreotide therapy
2个月前
已完结
Transforming advancing autosomal dominant polycystic kidney disease care: investigating new horizons in treatment and research
2个月前
已完结
Establishment of Membrane-Bound IgA1-Specific Antibody Possessing Antibody-Dependent Cellular Cytotoxicity Activity
2个月前
已完结