Lv61
1930 积分 2023-12-11 加入
In vivo endosomal escape assay identifies mechanisms for efficient hepatic LNP delivery
3小时前
已完结
A systematic review of the biodistribution of biomimetic high-density lipoproteins in mice
9天前
已完结
Mechanistic Pharmacokinetics and Pharmacodynamics of GalNAc-siRNA: Translational Model Involving Competitive Receptor-Mediated Disposition and RISC-Dependent Gene Silencing Applied to Givosiran
12天前
已完结
Predicting Clinical Pharmacokinetics/Pharmacodynamics and Impact of Organ Impairment on siRNA‐Based Therapeutics Using a Mechanistic Physiologically‐Based Pharmacokinetic‐Pharmacodynamic Model
12天前
已完结
Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N-Acetylgalactosamine–Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans
13天前
已完结
Targeted Delivery of Antisense Oligonucleotides Through Angiotensin Type 1 Receptor
21天前
已完结
Effect of pH-Responsive Ligands on mRNA Knockdown in EGFR-Targeting Ligand-Conjugated siRNAs
21天前
已完结
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
21天前
已完结
What Happens in Successful Optimizations? A Survey of 2018–2024 Literature
1个月前
已完结
Regulation of stem and progenitor cells in the adrenal cortex
1个月前
已完结
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