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Pyridones in drug discovery: Recent advances
4天前
已完结
Discovery of 1-Amino-1H-imidazole-5-carboxamide Derivatives as Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitors
24天前
已完结
Addition of benzyl ethers to alkynes: a metal-free synthesis of 1H-isochromenes
2个月前
已完结
Synthesis of 1H-Isochromenes and 1,2-Dihydroisoquinolines by Indium(III)-Catalyzed Cycloisomerization of ortho-(Alkynyl)benzyl Derivatives
2个月前
已完结
Property-based optimisation of PROTACs
3个月前
已完结
Study on Integrated Synthesis of Dimeric Pyranonaphthoquinones: Preparation of Versatile Synthetic Intermediate and Conversion into ent-Hemi-actinorhodin and ent-Hemi-γ-actinorhodin
3个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
4个月前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
4个月前
已完结
Regulated bioanalysis of antibody-drug conjugates using LC-MS
5个月前
已完结
Safety, pharmacokinetics, and antitumour activity of trastuzumab deruxtecan (DS-8201), a HER2-targeting antibody–drug conjugate, in patients with advanced breast and gastric or gastro-oesophageal tumours: a phase 1 dose-escalation study
5个月前
已完结
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