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976 积分 2025-09-10 加入
A map of molecular drug targets and therapeutics for the US FDA-approved drugs: The impact of expedited regulatory pathways and first-in-class drug approvals on drug innovation
2小时前
已完结
An overview of FDA-approved new molecular entities: 1827–2013
2小时前
已完结
Identification of an allosteric site on the E3 ligase adapter cereblon
14天前
已完结
A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson’s Disease
14天前
已完结
Heteroaryl Glutarimides and Dihydrouracils as Cereblon Ligand Scaffolds for Molecular Glue Degrader Discovery
1个月前
已完结
Carbon–Nitrogen Bond Formation Using Sodium Hexamethyldisilazide: Solvent-Dependent Reactivities and Mechanisms
1个月前
已完结
Site-Directed Fragment-Based Screening for the Discovery of Protein–Protein Interaction Stabilizers
1个月前
已完结
Long-acting GIPR agonist LY3537021 reduces body weight and fasting blood glucose in patients with T2D: Preclinical development and phase 1 randomized ascending dose studies
2个月前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
2个月前
已完结
Pyruvic acid or DBU/O2 guided organophotoredox-catalyzed direct C–H alkylation/α-aminoalkylation of 1,2,4-triazine-3,5(2H,4H)-diones with amines
2个月前
已完结
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