Lv3
338 积分 2025-10-29 加入
Circular Bivalent Aptamer Chimeras Leveraging LDLR-Mediated Lysosomal Shuttling for Targeted Protein Degradation
22天前
已完结
Research Advances in Chaperone-Mediated Autophagy (CMA) and CMA-Based Protein Degraders
25天前
已完结
Structure-Guided Optimization of p62-Directed AUTOTACs for Efficient EGFR/VEGFR2 Degradation and Antitumor Efficacy
1个月前
已完结
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
4个月前
已完结
A Phase I Study of FHD-609, a Heterobifunctional Degrader of Bromodomain-Containing Protein 9, in Patients with Advanced Synovial Sarcoma or SMARCB1-Deficient Tumors
5个月前
已完结
Aberrant activation of m6A demethylase FTO renders HIF2α low/− clear cell renal cell carcinoma sensitive to BRD9 inhibitors
5个月前
已完结
New leap of BRD9 inhibitor: Imidazole substituents making BRD9 inhibitors excellent drug candidates for AML
8个月前
已关闭
Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes
8个月前
已完结
Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes
8个月前
已完结
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
9个月前
已完结
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