Lv5
1018 积分 2021-06-15 加入
Bispecific T cell engager therapy for refractory rheumatoid arthritis
2天前
已完结
Self-amplifying mRNA nanovaccine encoding GM-CSF-fused HPV16 E7 enhances immunogenicity and therapeutic efficacy against cervical cancer
7天前
已完结
Pharmaceutical Industry Perspectives on Exposure-Response Confounding in Large Molecule Therapeutics: Results From an IQ Consortium Survey
10天前
已完结
Translational Pharmacokinetic/Pharmacodynamic Modeling to Inform Target Concentration and Dose Projection of A Novel Selective Estrogen Receptor Degrader (SIM0270) for Early Clinical Development
17天前
已完结
An Innovative Approach to Optimize First‐In‐Human Minimal Anticipated Biological Effect Level Based Starting Dose in Oncology Trials for Bispecific T‐Cell Engagers: Experience from A Solid Tumor Bispecific T‐Cell Engager
1个月前
已完结
Application of a MABEL Approach for a T-Cell-Bispecific Monoclonal Antibody: CEA TCB
1个月前
已完结
A phase I toxicity, pharmacology, and dosimetry trial of monoclonal antibody OKB7 in patients with non-Hodgkin's lymphoma: effects of tumor burden and antigen expression
1个月前
已完结
Treatment-induced and Pre-existing Anti-peg Antibodies: Prevalence, Clinical Implications, and Future Perspectives
1个月前
已完结
Characterization of CAR-T cellular kinetics and efficacy in solid tumor patients with and without prior lymphodepletion chemotherapy using a PBPK-PD model
1个月前
已完结
Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model
1个月前
已完结
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