Lv52
1398 积分 2024-11-01 加入
Discovery of Highly Efficacious CRBN-Based KRAS Degraders Targeting Cancers with KRAS G12D and G12V Mutations
7小时前
已完结
Discovery of AMG 133, a Glucose-Dependent Insulinotropic Polypeptide Receptor Antagonist and Glucagon-Like Peptide 1 Receptor Agonist Antibody-Drug Conjugate for the Treatment of Obesity
8小时前
已完结
From RAS inhibitor resistance to rational combination strategies
1天前
已完结
Chemical Linkers in Antibody–Drug Conjugates (ADCs)
23天前
已完结
New payloads drive next-gen antibody–drug conjugates
29天前
已完结
Design and characterization of PROTAC degraders specific to protein N-terminal methyltransferase 1
1个月前
已完结
N-myristoyltransferase-mediated protein myristoylation: molecular mechanisms, pathological roles, and targeted therapeutic strategies
1个月前
已关闭
Molecular Design and Preclinical Evaluation of GenSci143, a Novel B7-H3- and PSMA-Directed Bispecific Antibody-Drug Conjugate, for the Treatment of Prostate Cancer
1个月前
已完结
Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models
1个月前
已完结
DS-7300a, a novel B7-H3-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd, exhibits potent anti-tumor effects in nonclinical models
1个月前
已完结
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