Lv3
386 积分 2023-12-29 加入
Discovery of 2H-Pyrrolo[3,4- c ]pyridin-3-one Derivatives as Type-III c-MET Inhibitors Enabled by Free-Energy Perturbation Calculations
5天前
已完结
Rational Design and Optimization of Highly Selective CSF1R Inhibitors for the Treatment of Acute Liver Injury
6天前
已完结
Design, synthesis and bioevaluation of PI3Kα-selective inhibitors as potential colorectal cancer drugs
6天前
已完结
From Hit to Lead: Discovery of Novel Selective RIPK1 Inhibitor with Pyridoimidazole Scaffold for the Treatment of Autoimmune Diseases through Phenotypic Screening and Structural Optimization
6天前
已完结
Discovery of INCB191358: A Potent and Selective DGKα/ζ Dual Inhibitor
1个月前
已完结
Discovery of a Highly Potent and Selective mTOR Inhibitor that Strongly Suppresses Glioblastoma Multiforme Cell Growth
1个月前
已完结
Discovery of 6-Formylpyridyl Urea Derivatives as Potent Reversible-Covalent Fibroblast Growth Factor Receptor 4 Inhibitors with Improved Anti-Hepatocellular Carcinoma Activity
1个月前
已完结
Deciphering the mechanism of HM43239 inhibiting the mutant F691L resistant to gilteritinib in FMS-like tyrosine kinase 3
1个月前
已完结
Discovery of FLC-8 as the First Covalent FLT3 Inhibitor Targeting Cys807 for FLT3 Mutant Acute Myeloid Leukemia
1个月前
已完结
Efficient and Scalable Synthesis of a Novel Selective PI3Kα Inhibitor XJTU-L453
2个月前
已完结
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