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28 积分 2025-01-25 加入
Inhibitory effects of the main metabolites of Apatinib on CYP450 isozymes in human and rat liver microsomes
8天前
已完结
Drug-induced enzyme activity inhibition and CYP3A4 genetic polymorphism significantly shape the metabolic characteristics of furmonertinib
2个月前
已完结
Befotertinib: First Approval
2个月前
已完结
Validation of population pharmacokinetic models: a comparison of internal and external validation approaches for hydrochlorothiazide
3个月前
已完结
THE METABOLIC DISPOSITION OF APREPITANT, A SUBSTANCE P RECEPTOR ANTAGONIST, IN RATS AND DOGS
4个月前
已完结
Effects of Cytochrome P450 enzymes and drug–drug interaction on donafenib metabolism: in vivo, in vitro and in silico
4个月前
已完结
Development, validation and application of a UPLC-MS/MS method for simultaneous quantification of OPC-61815 and its metabolites tolvaptan, DM-4103 and DM-4107 in human plasma
4个月前
已完结
Simple Liquid Chromatography–Tandem Mass Spectrometry Method for Quantitation of Total and Free Aprepitant and Its Active N-Dealkylated Metabolites in Human Plasma
4个月前
已完结
Development of an UPLC-MS/MS method for quantification of donafenib and its metabolite in rat plasma: application to drug–drug interaction
5个月前
已完结
Qualitative and Quantitative Assessment of Drug-Drug Interaction Potential in Man, Based on Ki, IC50 and Inhibitor Concentration
5个月前
已完结
Deep Reinforcement Learning-Based Dynamic Reconfiguration Planning for Digital Twin-Driven Smart Manufacturing Systems With Reconfigurable Machine Tools
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