Lv51
1014 积分 2024-04-24 加入
An exatecan derivative based linker-payload platform leads to ADC products with promising anti-tumor efficacy and potential low interstitial lung disease (ILD) risk
2天前
已完结
The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients—The Putative Mechanism Behind ILD
3天前
已完结
Perivascular Niche–Resident Alveolar Macrophages Promote Interstitial Pneumonitis Related to Trastuzumab Deruxtecan Treatment
3天前
已完结
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
5天前
已完结
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy
5天前
已完结
Design and Preclinical Evaluation of a Novel B7-H4–Directed Antibody–Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305
9天前
已完结
Deubiquitinase-Targeting Chimeras Mediated Stabilization of Tumor Suppressive E3 Ligase Proteins as a Strategy for Cancer Therapy
3个月前
已完结
The Medicinal Chemist's Guide to Solving ADMET Challenges
3个月前
已完结
Design and Application of Cereblon-Recruiting Prodegraders
3个月前
已完结
Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability
3个月前
已完结
β1 integrin is a crucial regulator of pancreatic β-cell expansion
3个月前
已采纳
Effects of post-deposition annealing and copper inclusion in superstrate Sb2Se3 based solar cells by thermal evaporation
4个月前
已采纳
Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype
4个月前
已采纳
Quantum sieving: feasibility and challenges for the separation of hydrogen isotopes in nanoporous materials
4个月前
已采纳
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway
4个月前
已采纳
Fast Room-Temperature Synthesis of an Extremely Alkaline-Resistant Cationic Metal–Organic Framework for Sequestering TcO4− with Exceptional Selectivity
4个月前
已采纳
OsTTL的磷酸化促进了其泛素化降解
5个月前
已采纳
Nano‐Econazole Enhanced PD‐L1 Checkpoint Blockade for Synergistic Antitumor Immunotherapy against Pancreatic Ductal Adenocarcinoma
5个月前
已采纳
Bidirectional rotating biatrial tachycardia
5个月前
已采纳
Mild Crohn’s disease is associated with altered sphingolipid metabolism and reduced neutrophilic inflammation
5个月前
已采纳
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