Lv21
116 积分 2025-06-23 加入
Sulfoximines as Secondary Sulfonamide Isosteres: Paradoxical Impact on Solubility and Plasma Protein Binding
2小时前
已完结
Discovery and preclinical evaluations of TQB3616, a novel CDK4-biased inhibitor
1个月前
已完结
Reappraising Dichloromethane: Uncovering a Hidden Coupling Reagent for Activating Carboxylic Acids in Direct Amide Synthesis
1个月前
已完结
Cross-Electrophile Coupling of Challenging 5-Membered Heteroaryl Bromides with Alkyl Electrophiles
2个月前
已完结
Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
2个月前
已完结
KATs in the MYST: A New Therapeutic Vulnerability for SETBP1 -Mutated Myeloid Malignancies
2个月前
已完结
EMERGING MEDICINAL CHEMISTRY APPROACHES TO MODULATE TRANSCRIPTIONAL ACTIVITY BY ACETYLATION
3个月前
已完结
Kinase-deficient BTK mutants confer ibrutinib resistance through activation of the kinase HCK
3个月前
已完结
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
4个月前
已完结
DeepDegradome: A structure-aware deep learning framework for PROTAC and ligand generation against protein targets
4个月前
已完结
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