Lv6
2340 积分 2023-03-12 加入
In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment
23天前
已完结
Antibody drug conjugates beyond cytotoxic payloads
30天前
已完结
Molecular analysis and therapeutic applications of human serum albumin-fatty acid interactions
1个月前
已完结
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies
1个月前
已完结
The evolving landscape of CDK inhibitor use in breast cancer therapy and beyond
1个月前
已完结
Utilizing Molecular Dynamics and Mechanistic Pharmacokinetic Studies in the Design of Selective CDK2 Inhibitors
2个月前
已完结
PRMT5: A Promising Synthetical Lethal Target for MTAP-Deleted Cancers
2个月前
已完结
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers
2个月前
已完结
146 (PB134): First disclosure of AZD3470, a highly potent MTA-cooperative PRMT5 inhibitor in PRIMROSE and PRIMAVERA clinical studies
2个月前
已完结
Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation
3个月前
已完结
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